1-Adamantanol CAS NO.768-95-6

1. Introduction of 1-Adamantanol
1-Adamantanol is also called Tricyclo[3.3.1.1(3,7)]decan-1-ol ; Tricyclo[3.3.1.1]decan-1-ol ; 1-Adamantol ; 1-Adamatanol ; Damantol-(1) ; Tricyclo(3.3.1.1(sup3,7))decan-1-ol ; 1-Hydroxydiamantane.

2. Properties of 1-Adamantanol
Melting Point: 247 °C (subl.)(lit.)
Flash Point: 240°C
Boiling Point: 245.8 °C at 760 mmHg
Freely Rotating Bonds: 1
Polar Surface Area: 9.23 Å2
Index of Refraction: 1.58
Molar Refractivity: 43.71 cm3
Molar Volume: 131.1 cm3
Surface Tension: 49.3 dyne/cm
Enthalpy of Vaporization: 56.11 kJ/mol
Vapour Pressure: 0.00466 mmHg at 25°C
Appearance: white to off-white crystalline powder or needles

3. Structure Descriptors of 1-Adamantanol
InChI=1S/C10H16O/c11-10-4-7-1-8(5-10)3-9(2-7)6-10/h7-9,11H,1-6H2

4. Toxicity of 1-Adamantanol

 

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
mouse	LD50	intraperitoneal	600mg/kg (600mg/kg)		Pharmaceutical Chemistry Journal Vol. 10, Pg. 454, 1976.

5. Safety Information of 1-Adamantanol
Hazard Codes: Xi
Risk Statements: 36/37/38
R36/37/38: Irritating to eyes, respiratory system and skin.
Safety Statements: 22-24/25-36-26 begin_of_the_skype_highlighting 22-24/25-36-26 免费  end_of_the_skype_highlighting
S22: Do not breathe dust.
S24/25: Avoid contact with skin and eyes. 
S36: Wear suitable protective clothing. 
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
WGK Germany: 3
RTECS: AU4980000
Hazard Note: Irritant
HS Code: 29061900

6. Use of 1-Adamantanol
1-Adamantanol is used to make adamantane derivatives and adapalene.

7. Storage and transportation of 1-Adamantanol
Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Avoid to contact water or moisture during storing and transporting.

 

1. Introduction of 1-Adamantanol
1-Adamantanol is also called Tricyclo[3.3.1.1(3,7)]decan-1-ol ; Tricyclo[3.3.1.1]decan-1-ol ; 1-Adamantol ; 1-Adamatanol ; Damantol-(1) ; Tricyclo(3.3.1.1(sup3,7))decan-1-ol ; 1-Hydroxydiamantane.

2. Properties of 1-Adamantanol
Melting Point: 247 °C (subl.)(lit.)
Flash Point: 240°C
Boiling Point: 245.8 °C at 760 mmHg
Freely Rotating Bonds: 1
Polar Surface Area: 9.23 Å2
Index of Refraction: 1.58
Molar Refractivity: 43.71 cm3
Molar Volume: 131.1 cm3
Surface Tension: 49.3 dyne/cm
Enthalpy of Vaporization: 56.11 kJ/mol
Vapour Pressure: 0.00466 mmHg at 25°C
Appearance: white to off-white crystalline powder or needles

3. Structure Descriptors of 1-Adamantanol
InChI=1S/C10H16O/c11-10-4-7-1-8(5-10)3-9(2-7)6-10/h7-9,11H,1-6H2

4. Toxicity of 1-Adamantanol

 

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
mouse	LD50	intraperitoneal	600mg/kg (600mg/kg)		Pharmaceutical Chemistry Journal Vol. 10, Pg. 454, 1976.

5. Safety Information of 1-Adamantanol
Hazard Codes: Xi
Risk Statements: 36/37/38
R36/37/38: Irritating to eyes, respiratory system and skin.
Safety Statements: 22-24/25-36-26 begin_of_the_skype_highlighting 22-24/25-36-26 免费  end_of_the_skype_highlighting
S22: Do not breathe dust.
S24/25: Avoid contact with skin and eyes. 
S36: Wear suitable protective clothing. 
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
WGK Germany: 3
RTECS: AU4980000
Hazard Note: Irritant
HS Code: 29061900

6. Use of 1-Adamantanol
1-Adamantanol is used to make adamantane derivatives and adapalene.

7. Storage and transportation of 1-Adamantanol
Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Avoid to contact water or moisture during storing and transporting.